My son in law had an operation then, the problem was resolved and he's no longer on Eliquis. A couple of years ago, my daughter found a doctor in Texas and when he examined my son in law, he found that there was a genetic factor. My doctor did reduced the dosage from 20 mg daily to 15 mg. My children don't want me to be off this either, what if I have another TIA again, or worse, a stroke. I asked to ba taken off Xeralto since so far there's no sign of afib, but he doesn't think it's a good idea. I also had a loop recorder put in to monitor my HR. Read more: Bleeding Risk of Anticoagulants.I do not have afib, but I had a TIA in January so my cardiologist put me on Xeralto. Though they are certainly better than having an A-Fib stroke, they carry their own risks. Taking an anticoagulant is not like taking a multi-vitamin.Īnticoagulants work by causing or increasing bleeding. Anticoagulants are Still Considered High Risk DrugsĮven though Xarelto and Eliquis join Pradaxa with an antidote reversal agent, they are all still considered high-risk drugs. that Pradaxa can produce in some people.Įven if you seem to tolerate Pradaxa well, it may cause permanent GI damage over time.
Pradaxa’s own fact sheet states common side effects of Pradaxa include: For more see my article: The New Anticoagulants. A large number of patients on the 150mg dose of Pradaxa had an increased incidence of gastrointestinal adverse reactions (35%/yr) compared to warfarin (24%/yr). See my article: Pradaxa and the Other New Anticoagulants.)Īre you tolerating Pradaxa well ? Nearly two out of five people (35%) couldn’t― that’s a high rate of adverse reactions. (Note: Eliquis tested the best and is the safest of the new anticoagulants.
If you are taking Pradaxa, you may want to discuss with your doctor whether you should switch to another NOAC. It probably won’t be available till early June.Īndexxa rapidly and significantly reverses ‘anti-factor Xa’ activity which is the anticoagulant mechanism of both Xarelto and Eliquis. Now both Xarelto (rivaroxaban) and Eliquis (apixaban) have the FDA-approved reversal agent Andexxa (Portola Pharmaceuticals) as of May 7, 2018. Andexxa: Antidote for Xarelto and Eliquis Many patients with Atrial Fibrillation were put on Pradaxa rather than Xarelto and Eliquis because Pradaxa has had a reversal agent since 2015. Up to now, only the anticoagulants Pradaxa (dabigatran) and Coumadin (warfarin) had a reversal agent or antidote.Īs an example, if you were taking Pradaxa and were injured in an auto accident, doctors in the ER could administer ‘Praxbind’ (idarucizumab), the Pradaxa reversal agent, to stop any uncontrolled bleeding and (probably) save your life. An estimated 4 million people are taking factor Xa inhibitors. alone in 2016, there were about 117,000 hospital admissions attributed to factor Xa inhibitor-related bleeding and nearly 2,000 bleeding-related deaths per month. Since the introduction of the NOAC anticoagulants, there’s been an increase of hospital admissions and deaths related to bleeding, one of the major complications of anticoagulation. Walter Kerwin, MD, Cedars-Sinai Medical Center, Los Angeles, CAīackground: One of the problems for Atrial Fibrillation patients taking anticoagulants is the risk of life threatening or uncontrolled bleeding, particularly if one is injured. Steve Ryan, PhD, provides a comprehensive guide for persons seeking to find a cure for their Atrial Fibrillation." "Within the pages of Beat Your A-Fib, Dr. This is not an easy thing to do, but you have been very, very successful at it." You managed to combine an encyclopedic compilation of information with the simplicity of presentation that enhances the delivery of the information to the reader. She loves it and finds it very useful to help her in dealing with atrial fibrillation." "Dear Steve, I saw a patient this morning with your book and highlights throughout. Professor of Cardiology, Haut-Lévêque Hospital, Bordeaux, France I certainly recommend it for patients who want to know more about atrial fibrillation than what they will learn from doctors." "This book is incredibly complete and easy-to-understand for anybody. "If I had 10 years ago, it would have saved me 8 years of hell.” Doctors & patients are saying about 'Beat Your A-Fib'.
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